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Article

Sperm gene expression profile is related to pregnancy rate after insemination and is predictive of low fecundity in normozoospermic men

23 Mar 2012

Abstract excerpt

BACKGROUND: Assessment of male fertility is traditionally based on microscopic evaluation of semen. However, the classical semen parameters do not adequately reflect sperm function, and their clinical value in predicting fertility is limited. We hypothesize that the sperm expression profile could reflect the fertilizing quality of spermatozoa and could be more informative for predicting the in vivo reproductive...

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PMID: 22447625
DOI: 10.1093/humrep/des074

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