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Article

Maternal inheritance of a promoter variant in the imprinted PHLDA2 gene significantly increases birth weight.

American journal of human genetics - 6 Apr 2012

Ishida Miho, Monk David, Duncan Andrew J, Abu-Amero Sayeda, Chong Jiehan, Ring Susan M, Pembrey Marcus E, Hindmarsh Peter C, Whittaker John C, Stanier Philip, Moore Gudrun E

Abstract excerpt

Birth weight is an important indicator of both perinatal and adult health, but little is known about the genetic factors contributing to its variability. Intrauterine growth restriction is a leading cause of perinatal morbidity and mortality and is also associated with adult disease. A significant correlation has been reported between lower birth weight and increased expression of the maternal PHLDA2 allele in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22444668
DOI: 10.1016/j.ajhg.2012.02.021
PMCID: PMC3322226

Genes

PHLDA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Maternal inheritance of a promoter variant in the imprinted PHLDA2 gene significantly increases birth weight.PMID 22444668Read ↗

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