Article
Fibrin formation by staphylothrombin facilitates Staphylococcus aureus-induced platelet aggregation.
Thrombosis and haemostasis - 1 Jun 2012
Vanassche Thomas, Kauskot Alexandre, Verhaegen Jan, Peetermans Willy E, van Ryn Joanne, Schneewind Olaf, Hoylaerts Marc F, Verhamme Peter
Abstract excerpt
Interactions of Staphylococcus aureus (S. aureus) and platelets play an important role in the pathogenesis of intravascular infections such as infective endocarditis (IE). A typical feature of S. aureus is the ability to generate thrombin activity through the secretion of two prothrombin activati...
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