Article
A novel X-linked combined immunodeficiency disease.
The Journal of clinical investigation - 1 Nov 1990
Brooks E G, Schmalstieg F C, Wirt D P, Rosenblatt H M, Adkins L T, Lookingbill D P, Rudloff H E, Rakusan T A, Goldman A S
Abstract excerpt
A novel X-linked combined immunodeficiency disease was found in five living males in an extended family in the United States. The age of the affected males ranged from 2.5 to 34 yr. The most prominent clinical abnormalities were a paucity of lymphoid tissue; recurrent sinusitis, otitis media, bro...
Topics
- Adolescent
- Adult
- Child
- Child, Preschool
- Female
- Genetic Linkage
- Humans
- Immunoglobulins
- Immunologic Deficiency Syndromes
- Leukocyte Count
- Male
- Pedigree
- Phenotype
- T-Lymphocytes
- X Chromosome