Article
[Achetylcholinesterase (AChE) inhibition and serum lipokines in Alzheimer's disease: friend or foe?].
Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology - 1 Mar 2012
Kovacs Janos, Pakaski Magdolna, Juhasz Anna, Feher Agnes, Drotos Gergely, Fazekas Csilla Orsike, Horvath Tamas Laszlo, Janka Zoltan, Kalman Janos
Abstract excerpt
Throughout the natural progression of Alzheimer's disease (AD), the body mass index (BMI) decreases. This is believed to be brought on by the disturbance in the central lipid metabolism, but the exact mechanism is yet unknown. Adipokines (adiponectin, leptin), hormones produced by the adipose tissue, change glucose and lipid metabolism, and have an anorectic effect through increasing energy consumption in the...
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