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Article

A non-Mendelian MAPK-generated hereditary unit controlled by a second MAPK pathway in Podospora anserina.

Genetics - 1 Jun 2012

Lalucque Hervé, Malagnac Fabienne, Brun Sylvain, Kicka Sébastien, Silar Philippe

Abstract excerpt

The Podospora anserina PaMpk1 MAP kinase (MAPK) signaling pathway can generate a cytoplasmic and infectious element resembling prions. When present in the cells, this C element causes the crippled growth (CG) cell degeneration. CG results from the inappropriate autocatalytic activation of the PaMpk1 MAPK pathway during growth, whereas this cascade normally signals stationary phase. Little is known about the...

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Identifiers

PMID: 22426880
DOI: 10.1534/genetics.112.139469
PMCID: PMC3374308

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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