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Article

Endothelial nitric oxide synthase intron 4 VNTR gene polymorphisms in European and African populations.

Molecular biology reports - 1 Jun 2012

Santovito Alfredo, Cervella Piero, Delpero Massimiliano

Abstract excerpt

Endogenous nitric oxide (NO) is a molecule synthesized by endothelium nitric oxide synthase encoded by the ecNOS gene that plays an important role in regulating the systemic, cardiac and pulmonary circulation. Impairment in NO synthesis has been associated to many cardiovascular disorders, including coronary artery disease and hypertension. We investigated the frequency of the intron 4 VNTR ecNOS gene...

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PMID: 22422158
DOI: 10.1007/s11033-012-1492-4

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