Article
Antibodies binding to citrullinated telopeptides of type I and type II collagens and to mutated citrullinated vimentin synergistically predict the development of seropositive rheumatoid arthritis.
Annals of the rheumatic diseases - 1 Oct 2012
Koivula Marja-Kaisa, Heliövaara Markku, Rissanen Harri, Palosuo Timo, Knekt Paul, Immonen Heikki, Risteli Juha
Abstract excerpt
OBJECTIVE: To assess whether antibodies binding to citrullinated carboxy-terminal telopeptides of type I and type II collagens (TELO-I and TELO-II, respectively), mutated citrullinated vimentin (MCV) and cyclic citrullinated peptides (CCP) predict the development of rheumatoid arthritis (RA). METHODS: A case-control study was nested within a Finnish cohort of 36 000 adults who had neither arthritis nor a history...
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