Article
Molecular mapping of high-grade cervical intraepithelial neoplasia shows etiological dominance of HPV16.
International journal of cancer - 15 Sept 2012
van der Marel Jacolien, Quint Wim G V, Schiffman Mark, van de Sandt Miekel M, Zuna Rosemary E, Dunn S Terence, Smith Katherine, Mathews Cara A, Gold Michael A, Walker Joan, Wentzensen Nicolas
Abstract excerpt
Women with high-grade cervical intraepithelial neoplasia (HGCIN) frequently present with multiple cervical lesions and multiple concomitant Human papillomavirus (HPV) genotype infections. To elucidate HPV genotype attribution in different regions on the cervix, we performed molecular mapping of cervical disease in women with HGCIN. Thirteen subjects referred to colposcopy for abnormal cervical cancer screening...
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