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Article

Enteropathogenic Escherichia coli inhibits ileal sodium-dependent bile acid transporter ASBT.

American journal of physiology. Gastrointestinal and liver physiology - 15 May 2012

Annaba Fadi, Sarwar Zaheer, Gill Ravinder K, Ghosh Amit, Saksena Seema, Borthakur Alip, Hecht Gail A, Dudeja Pradeep K, Alrefai Waddah A

Abstract excerpt

Apical sodium-dependent bile acid transporter (ASBT) is responsible for the absorption of bile acids from the intestine. A decrease in ASBT function and expression has been implicated in diarrhea associated with intestinal inflammation. Whether infection with pathogenic microorganisms such as the enteropathogenic Escherichia coli (EPEC) affect ASBT activity is not known. EPEC is a food-borne enteric pathogen that...

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Identifiers

PMID: 22403793
DOI: 10.1152/ajpgi.00017.2012
PMCID: PMC3362099

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