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Article

Novel deletion mutations of OPTN in amyotrophic lateral sclerosis in Japanese.

Neurobiology of aging - 1 Aug 2012

Iida Aritoshi, Hosono Naoya, Sano Motoki, Kamei Tetsumasa, Oshima Shuichi, Tokuda Torao, Nakajima Masahiro, Kubo Michiaki, Nakamura Yusuke, Ikegawa Shiro

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by selective motor neuron death in the brain and spinal cord. Many disease genes for ALS have been identified; however, each disease gene is responsible for very small fractions of ALS. Recently, mutations of t...

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Source

Identifiers

PMID: 22402017
DOI: 10.1016/j.neurobiolaging.2011.12.037

Genes

OPTN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22402017-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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