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Article

Intracellular inflammatory sensors for foreign invaders and substances of self-origin.

Advances in experimental medicine and biology - 1 Jan 2012

Jounai Nao, Kobiyama Kouji, Takeshita Fumihiko

Abstract excerpt

In order to survive, all organisms must recognize and eliminate foreign invaders such as infectious pathogens, chemicals, ultraviolet rays, metabolites and damaged or transformed self-tissues, as well as allogenic organs in cases of transplantation. Recent research in innate immunity has elucidated that there are versatile inflammatory sensors on spatiotemporal 'sentry duty' that recognize substances derived from...

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PMID: 22399374
DOI: 10.1007/978-1-4614-1680-7_5

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