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Article

Influenza virus sequence feature variant type analysis: evidence of a role for NS1 in influenza virus host range restriction.

Journal of virology - 1 May 2012

Noronha Jyothi M, Liu Mengya, Squires R Burke, Pickett Brett E, Hale Benjamin G, Air Gillian M, Galloway Summer E, Takimoto Toru, Schmolke Mirco, Hunt Victoria, Klem Edward, García-Sastre Adolfo, McGee Monnie, Scheuermann Richard H

Abstract excerpt

Genetic drift of influenza virus genomic sequences occurs through the combined effects of sequence alterations introduced by a low-fidelity polymerase and the varying selective pressures experienced as the virus migrates through different host environments. While traditional phylogenetic analysis is useful in tracking the evolutionary heritage of these viruses, the specific genetic determinants that dictate...

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Identifiers

PMID: 22398283
DOI: 10.1128/JVI.06901-11
PMCID: PMC3347290

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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