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Article

Differential binding between PatS C-terminal peptide fragments and HetR from Anabaena sp. PCC 7120.

Biochemistry - 27 Mar 2012

Feldmann Erik A, Ni Shuisong, Sahu Indra D, Mishler Clay H, Levengood Jeffrey D, Kushnir Yegor, McCarrick Robert M, Lorigan Gary A, Tolbert Blanton S, Callahan Sean M, Kennedy Michael A

Abstract excerpt

Heterocyst differentiation in the filamentous cyanobacterium Anabaena sp. strain PCC 7120 occurs at regular intervals under nitrogen starvation and is regulated by a host of signaling molecules responsive to availability of fixed nitrogen. The heterocyst differentiation inhibitor PatS contains the active pentapeptide RGSGR (PatS-5) at its C-terminus considered the minimum PatS fragment required for normal...

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PMID: 22397695
DOI: 10.1021/bi300228n

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Differential binding between PatS C-terminal peptide fragments and HetR from Anabaena sp. PCC 7120.PMID 22397695Read ↗

Evidence for direct binding between HetR from Anabaena sp. PCC 7120 and PatS-5.Semantic proximity Read ↗

Different functions of HetR, a master regulator of heterocyst differentiation in Anabaena sp. PCC 7120, can be separated by mutation.Semantic proximity Read ↗

Mutagenesis of hetR reveals amino acids necessary for HetR function in the heterocystous cyanobacterium Anabaena sp. strain PCC 7120.Semantic proximity Read ↗

Phenotypic Assessment Suggests Multiple Start Codons for HetN, an Inhibitor of Heterocyst Differentiation, in Anabaena sp. Strain PCC 7120.Semantic proximity Read ↗

HetF and PatA control levels of HetR in Anabaena sp. strain PCC 7120.Semantic proximity Read ↗

Heterocyst pattern formation controlled by a diffusible peptide.Semantic proximity Read ↗

Biased inheritance of the protein PatN frees vegetative cells to initiate patterned heterocyst differentiation.Semantic proximity Read ↗

Functional Overlap of hetP and hetZ in Regulation of Heterocyst Differentiation in Anabaena sp. Strain PCC 7120.Semantic proximity Read ↗

Mutation of sepJ reduces the intercellular signal range of a hetN-dependent paracrine signal, but not of a patS-dependent signal, in the filamentous cyanobacterium Anabaena sp. strain PCC 7120.Semantic proximity Read ↗

Epistasis analysis of four genes from Anabaena sp. strain PCC 7120 suggests a connection between PatA and PatS in heterocyst pattern formation.Semantic proximity Read ↗

Identification of a gene regulated by HetR, a master regulator of heterocyst differentiation, in the non-heterocyst-forming filamentous cyanobacterium Arthrospira platensis NIES-39.Semantic proximity Read ↗

Structures of complexes comprised of Fischerella transcription factor HetR with Anabaena DNA targets.Semantic proximity Read ↗

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