Article
Whole blood gene expression testing for coronary artery disease in nondiabetic patients: major adverse cardiovascular events and interventions in the PREDICT trial.
Journal of cardiovascular translational research - 1 Jun 2012
Rosenberg Steven, Elashoff Michael R, Lieu Hsiao D, Brown Bradley O, Kraus William E, Schwartz Robert S, Voros Szilard, Ellis Stephen G, Waksman Ron, McPherson John A, Lansky Alexandra J, Topol Eric J
Abstract excerpt
The majority of first-time angiography patients are without obstructive coronary artery disease (CAD). A blood gene expression score (GES) for obstructive CAD likelihood was validated in the PREDICT study, but its relation to major adverse cardiovascular events (MACE) and revascularization was not assessed. Patients (N = 1,160) were followed up for MACE and revascularization 1 year post-index angiography and GES,...
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