Article
Rapid detection of drug resistance and mutational patterns of extensively drug-resistant strains by a novel GenoType® MTBDRsl assay.
Journal of postgraduate medicine - 1 Jan 2000
Singh A K, Maurya A K, Kant S, Umrao J, Kushwaha R A S, Nag V L, Dhole T N
Abstract excerpt
BACKGROUND: The emergence of extensively drug-resistant tuberculosis (XDR-TB) is a major concern in the India. The burden of XDR-TB is increasing due to inadequate monitoring, lack of proper diagnosis, and treatment. The GenoType ® Mycobacterium tuberculosis drug resistance second line (MTBDRsl) assay is a novel line probe assay used for the rapid detection of mutational patterns conferring resistance to XDR-TB....
Topics
- Amikacin
- Anti-Bacterial Agents
- DNA Gyrase
- Ethambutol
- Extensively Drug-Resistant Tuberculosis
- Fluoroquinolones
- Genotyping Techniques
- Humans
- Kanamycin
- Mutation
- Mycobacterium tuberculosis
- Pentosyltransferases
- Phenotype
- RNA, Ribosomal, 16S