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Article

Characterization of a recurrent poor-quality embryo morphology phenotype and zygote transfer as a rescue strategy.

Reproductive biomedicine online - 1 Apr 2012

Sermondade Nathalie, Delarouzière Vanina, Ravel Célia, Berthaut Isabelle, Verstraete Lieve, Mathieu Emmanuelle, Antoine Jean-Marie, Mandelbaum Jacqueline

Abstract excerpt

Some patients in IVF programmes repeatedly display an abnormal embryonic development characterized as soon as day 2 post fertilization by a high rate (>60%) of highly fragmented embryos (⩾40% of cytoplasmic fragments) leading to recurrent IVF failures. This study postulated that, for various maternal reasons, some embryos were unable to withstand the in-vitro environment and an early pronucleate-stage transfer...

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Source

Identifiers

PMID: 22377150
DOI: 10.1016/j.rbmo.2012.01.004

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