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Article

Capucin does not modify the toxicity of a mutant Huntingtin fragment in vivo.

Neurobiology of aging - 1 Aug 2012

Galvan Laurie, Lepejová Nad'a, Gaillard Marie-Claude, Malgorn Carole, Guillermier Martine, Houitte Diane, Bonvento Gilles, Petit Fanny, Dufour Noëlle, Héry Patrick, Gérard Matthieu, Elalouf Jean-Marc, Déglon Nicole, Brouillet Emmanuel, de Chaldée Michel

Abstract excerpt

Genes selectively expressed in the striatum may be involved in the preferential vulnerability of striatal neurons to Huntington's disease (HD). Here, we investigated whether perturbations of Capucin expression, which is enriched in the striatum and downregulated in Huntington's disease models, could modify the neurotoxicity induced by the injection of a lentiviral vector encoding a short N-terminal fragment of...

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PMID: 22365050
DOI: 10.1016/j.neurobiolaging.2012.01.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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