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Article

Essential role of microfibrillar-associated protein 4 in human cutaneous homeostasis and in its photoprotection

22 Nov 2011

Abstract excerpt

UVB-induced cutaneous photodamage/photoaging is characterized by qualitative and quantitative deterioration in dermal extracellular matrix (ECM) components such as collagen and elastic fibers. Disappearance of microfibrillar-associated protein 4 (MFAP-4), a possible limiting factor for cutaneous elasticity, was documented in photoaged dermis, but its function is poorly understood. To characterize its possible...

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PMID: 22355679
DOI: 10.1038/srep00164

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