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Article

Sequence analysis of Epstein-Barr virus EBNA-2 gene coding amino acid 148-487 in nasopharyngeal and gastric carcinomas.

Virology journal - 21 Feb 2012

Wang Xinying, Wang Yun, Wu Guocai, Chao Yan, Sun Zhifu, Luo Bing

Abstract excerpt

BACKGROUND: The Epstein-Barr virus (EBV) nuclear antigen 2 (EBNA-2) plays a key role in the B-cell growth transformation by initiating and maintaining the proliferation of infected B-cell upon EBV infection in vitro. Most studies about EBNA-2 have focused on its functions yet little is known for its intertypic polymorphisms. RESULTS: Coding region for amino acid (aa) 148-487 of the EBNA-2 gene was sequenced in 25...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22348267
DOI: 10.1186/1743-422X-9-49
PMCID: PMC3312847

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