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Article

Two-In-One: Combined Targeted Chemo and Gene Therapy for Tumor Suppression and Prevention of Metastases

1 Feb 2012

Abstract excerpt

AIMS: To develop an approach for the effective treatment of ovarian tumor, prevention of metastases and limitation of side effects. MATERIALS & METHODS: In order to combine chemotherapy with genotherapy, we constructed a nanoscale-based tumor-targeted system containing two anticancer drugs, two antisense oligonucleotides (suppressors of cellular resistance) and a ligand specific to receptors overexpressed in...

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Identifiers

PMID: 22339132
DOI: 10.2217/nnm.11.131

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