Article
Heterogeneity of the transition/transversion ratio in Drosophila and Hominidae genomes.
Molecular biology and evolution - 1 Aug 2012
Seplyarskiy Vladimir B, Kharchenko Peter, Kondrashov Alexey S, Bazykin Georgii A
Abstract excerpt
Mutation rate varies between sites in the genome. Part of this variation can be explained by well-recognized short nucleotide contexts, but a large component of this variation remains cryptic. We used data on interspecies divergence and intraspecies polymorphism in Drosophila and Hominidae to analyze variation of the average rate of the 12 possible kinds of single-nucleotide mutations and in the...
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