Article
Rodent models for human polycystic ovary syndrome.
Biology of reproduction - 1 May 2012
Walters Kirsty A, Allan Charles M, Handelsman David J
Abstract excerpt
Polycystic ovary syndrome (PCOS) is the most frequent female endocrine disorder, affecting 5%-10% of women, causing infertility due to dysfunctional follicular maturation and ovulation, distinctive multicystic ovaries and hyperandrogenism, together with metabolic abnormalities including obesity, hyperinsulinism, an increased risk of type 2 diabetes, and cardiovascular disease. The etiology of PCOS is unclear, and...
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