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Article

Liver involvement in children with Familial Mediterranean fever.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver - 1 Aug 2012

Unal Fatih, Cakir Murat, Baran Masallah, Arıkan Cigdem, Yuksekkaya Hasan Ali, Aydoğdu Sema

Abstract excerpt

AIM: Familial Mediterranean fever is characterised by recurrent, febrile, inflammatory attacks of the serosal membranes. Prolonged inflammatory response is triggered secondary to cytokine stimulation due to reduced activity of pyrin. Inflammatory cytokines play major role in the pathogenesis of acute liver injury; and chronic, recurrent cytokine production may cause chronic hepatitis/cirrhosis. We aimed to...

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Identifiers

PMID: 22333476
DOI: 10.1016/j.dld.2012.01.003

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