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Article

Associations of allergic sensitization and clinical phenotypes with innate immune response genes polymorphisms are modified by house dust mite allergen exposure

1 Jan 2011

Abstract excerpt

INTRODUCTION: Polymorphisms within innate immunity genes are associated with allergic phenotypes but results are variable. These associations were not analyzed with respect to allergen exposure. We investigated associations of TLR and CD14 polymorphisms with allergy phenotypes in the context of house dust mite (HDM) exposure. MATERIAL AND METHODS: Children, aged 12-16 years (n=326), were recruited from downtown...

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PMID: 22328887
DOI: 10.5114/aoms.2011.26616

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