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Article

Spliceman--a computational web server that predicts sequence variations in pre-mRNA splicing.

Bioinformatics (Oxford, England) - 1 Apr 2012

Lim Kian Huat, Fairbrother William Guy

Abstract excerpt

SUMMARY: It was previously demonstrated that splicing elements are positional dependent. We exploited this relationship between location and function by comparing positional distributions between all possible 4096 hexamers around a database of human splice sites. The distance measure used in this study found point mutations that produced higher distances disrupted splicing, whereas point mutations with smaller...

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Identifiers

PMID: 22328782
DOI: 10.1093/bioinformatics/bts074
PMCID: PMC3315715

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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