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Optineurin immunoreactivity in neuronal nuclear inclusions of polyglutamine diseases (Huntington’s, DRPLA, SCA2, SCA3) and intranuclear inclusion body disease

7 Feb 2012

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PMID: 22318854
DOI: 10.1007/s00401-012-0956-x

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Optineurin immunoreactivity in neuronal nuclear inclusions of polyglutamine diseases (Huntington’s, DRPLA, SCA2, SCA3) and intranuclear inclusion body diseasePMID 22318854Read ↗

Non-expanded polyglutamine proteins in intranuclear inclusions of hereditary ataxias – triple-labeling immunofluorescence studySemantic proximity Read ↗

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Multiple Proteinopathies in Familial ALS Cases With Optineurin Mutations.Semantic proximity Read ↗

Optineurin is co-localized with FUS in basophilic inclusions of ALS with FUS mutation and in basophilic inclusion body diseaseSemantic proximity Read ↗

Optineurin inclusions occur in a minority of TDP-43 positive ALS and FTLD-TDP cases and are rarely observed in other neurodegenerative disorders.Semantic proximity Read ↗

Optineurin deficiency disrupts phosphorylated tau proteostasis and clusterin expression in human neuronsSemantic proximity Read ↗

Optineurin and amyotrophic lateral sclerosis.Semantic proximity Read ↗

Nuclear bodies in neurodegenerative diseaseSemantic proximity Read ↗

Huntington's Disease Intranuclear Inclusions Contain Truncated, Ubiquitinated Huntingtin ProteinSemantic proximity Read ↗

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