Article
Evaluation and management of women with BRCA1/2 mutations.
Oncology (Williston Park, N.Y.) - 1 Oct 2005
Peshkin Beth N, Isaacs Claudine
Abstract excerpt
Genetic counseling and testing for susceptibility to breast and ovarian cancer is often an integral component of management for women with a personal and/or family history of these malignancies. In this article, we will briefly review the function and genetic epidemiology of the two major susceptibility genes, BRCA1 and BRCA2. We will then address approaches to risk assessment for women at high risk with respect...
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