Article
Host-pathogen coevolution in human tuberculosis.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 19 Mar 2012
Gagneux Sebastien
Abstract excerpt
Tuberculosis (TB) is a disease of antiquity. Yet TB today still causes more adult deaths than any other single infectious disease. Recent studies show that contrary to the common view postulating an animal origin for TB, Mycobacterium tuberculosis complex (MTBC), the causative agent of TB, emerged as a human pathogen in Africa and colonized the world accompanying the Out-of-Africa migrations of modern humans....
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