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Article

Primary human sinonasal epithelial cell culture model for topical drug delivery in patients with chronic rhinosinusitis with nasal polyposis.

The Journal of pharmacy and pharmacology - 1 Mar 2012

Bleier Benjamin S, Mulligan Ryan M, Schlosser Rodney J

Abstract excerpt

OBJECTIVES: The primary human sinonasal epithelial cell culture (HSNEC) allows for in-vitro modelling of mucosal responses to topical therapy. Cultures grown from healthy donors may underestimate changes in individuals with chronic sinonasal disease thereby yielding inaccurate results with respect to this large patient population. The purpose of this study was to analyse HSNECs derived from patients with chronic...

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Identifiers

PMID: 22309277
DOI: 10.1111/j.2042-7158.2011.01409.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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