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Nematode sperm maturation triggered by protease involves sperm-secreted serine protease inhibitor (Serpin)

17 Jan 2012

Abstract excerpt

Spermiogenesis is a series of poorly understood morphological, physiological and biochemical processes that occur during the transition of immotile spermatids into motile, fertilization-competent spermatozoa. Here, we identified a Serpin (serine protease inhibitor) family protein (As_SRP-1) that is secreted from spermatids during nematode Ascaris suum spermiogenesis (also called sperm activation) and we showed...

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PMID: 22307610
DOI: 10.1073/pnas.1109912109

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