Article
Trends of transmitted drug resistance of HIV-1 and its impact on treatment response to first-line antiretroviral therapy in Taiwan.
The Journal of antimicrobial chemotherapy - 1 May 2012
Lai Chung-Chih, Hung Chien-Ching, Chen Mao-Yuan, Sun Hsin-Yun, Lu Ching-Lan, Tseng Yu-Tzu, Chang Shu-Fang, Su Yi-Ching, Liu Wen-Chun, Hsieh Chia-Yin, Wu Pei-Ying, Chang Sui-Yuan, Chang Shan-Chwen
Abstract excerpt
OBJECTIVES: To determine the impact of transmitted drug resistance (TDR) of HIV-1 on treatment outcome in areas where routine testing for drug resistance mutations may not be available before combination antiretroviral therapy (cART) is initiated. METHODS: Genotypic resistance assays were performed on HIV isolates from archived blood samples obtained from 1349 antiretroviral-naive HIV-1-infected patients in...
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