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Article

Association of TMPRSS6 polymorphisms with ferritin, hemoglobin, and type 2 diabetes risk in a Chinese Han population.

The American journal of clinical nutrition - 1 Mar 2012

Gan Wei, Guan Yu, Wu Qian, An Peng, Zhu Jingwen, Lu Ling, Jing Li, Yu Yu, Ruan Sheng, Xie Dong, Makrides Maria, Gibson Robert A, Anderson Gregory J, Li Huaixing, Lin Xu, Wang Fudi

Abstract excerpt

BACKGROUND: Transmembrane protease serine 6 (TMPRSS6) regulates iron homeostasis by inhibiting the expression of hepcidin. Multiple common variants in TMPRSS6 were significantly associated with serum iron in recent genome-wide association studies, but their effects in the Chinese remain to be elucidated. OBJECTIVE: The objective was to determine whether the TMPRSS6 single nucleotide polymorphisms (SNPs)...

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Share to Antimicrobial Cationic Peptides
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22301935
DOI: 10.3945/ajcn.111.025684

Genes

TMPRSS6

Variants

rs855791
rs855791

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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