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Article

The effect of next-generation sequencing technology on complex trait research.

European journal of clinical investigation - 1 May 2011

Day-Williams Aaron G, Zeggini Eleftheria

Abstract excerpt

BACKGROUND: Advances in the understanding of complex trait genetics have always been enabled by advances in genomic technology. Next-generation sequencing (NGS) is set to revolutionize the way complex trait genetics research is carried out. RESULTS: NGS has multiple applications in the field of human genetics, but is accompanied by substantial study design, analysis and interpretation challenges. This review...

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PMID: 21155765
DOI: 10.1111/j.1365-2362.2010.02437.x
PMCID: PMC3107422

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