Article
The effect of next-generation sequencing technology on complex trait research.
European journal of clinical investigation - 1 May 2011
Day-Williams Aaron G, Zeggini Eleftheria
Abstract excerpt
BACKGROUND: Advances in the understanding of complex trait genetics have always been enabled by advances in genomic technology. Next-generation sequencing (NGS) is set to revolutionize the way complex trait genetics research is carried out. RESULTS: NGS has multiple applications in the field of human genetics, but is accompanied by substantial study design, analysis and interpretation challenges. This review...
Topics
- Disease
- Genetic Research
- Genome, Human
- Genomics
- Genotype
- Humans
- Research Design
- Sequence Analysis, DNA