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Article

Global analysis of DNA methylation in early-stage liver fibrosis

27 Jan 2012

Abstract excerpt

BACKGROUND: Liver fibrosis is caused by chemicals or viral infection. The progression of liver fibrosis results in hepatocellular carcinogenesis in later stages. Recent studies have revealed the importance of DNA hypermethylation in the progression of liver fibrosis to hepatocellular carcinoma (HCC). However, the importance of DNA methylation in the early-stage liver fibrosis remains unclear. METHODS: To address...

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Share to Epigenetics and DNA Methylation
Share to Hepatocellular Carcinoma Treatment and Prognosis
Share to Liver physiology and pathology

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PMID: 22281153
DOI: 10.1186/1755-8794-5-5

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