Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Riboswitch-Based Inducible Gene Expression System for Mycobacteria

18 Jan 2012

Abstract excerpt

Research on the human pathogen Mycobacterium tuberculosis (Mtb) would benefit from novel tools for regulated gene expression. Here we describe the characterization and application of a synthetic riboswitch-based system, which comprises a mycobacterial promoter for transcriptional control and a riboswitch for translational control. The system was used to induce and repress heterologous protein overexpression...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Genetics and Biotechnology
Share to RNA and protein synthesis mechanisms
Share to Tuberculosis Research and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22279533
DOI: 10.1371/journal.pone.0029266

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Riboswitch-Based Inducible Gene Expression System for MycobacteriaPMID 22279533Read ↗

Synthetic Riboswitches That Induce Gene Expression in Diverse Bacterial SpeciesSemantic proximity Read ↗

A VERSATILE LIBRARY OF TETRACYCLINE-INDUCIBLE AND REPRESSIBLE VECTORS FOR FINE-TUNED GENE EXPRESSIONSemantic proximity Read ↗

Riboswitches in unexpected places--a synthetic riboswitch in a protein coding region.Semantic proximity Read ↗

Reprogramming Mycobacterium Tuberculosis CRISPR System for Gene Editing and Genome-Wide RNA Interference ScreeningSemantic proximity Read ↗

Translational gene expression control in Chlamydia trachomatisSemantic proximity Read ↗

Translational gene expression control in <i>Chlamydia trachomatis</i>Semantic proximity Read ↗

Generation of orthogonally selective bacterial riboswitches by targeted mutagenesis and in vivo screening.Semantic proximity Read ↗

Requirements for efficient ligand-gated co-transcriptional switching in designed variants of the B. subtilis pbuE adenine-responsive riboswitch in E. coli.Semantic proximity Read ↗

Development of a repressible mycobacterial promoter system based on two transcriptional repressors.Semantic proximity Read ↗

Specialized transduction designed for precise high-throughput unmarked deletions in Mycobacterium tuberculosis.Semantic proximity Read ↗

Engineering complex riboswitch regulation by dual genetic selection.Semantic proximity Read ↗

An IPTG Inducible Conditional Expression System for Mycobacteria.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.