Article
Quadruplex real-time polymerase chain reaction assay for molecular diagnosis of Y-chromosomal microdeletions.
Fertility and sterility - 1 Apr 2012
Guo Qiwei, Lan Fenghua, Xu Liangpu, Jiang Yu, Xiao Li, Huang Hailong, Zhou Yulin
Abstract excerpt
OBJECTIVE: To develop a rapid and reliable method for molecular diagnosis of Y-chromosomal microdeletions. DESIGN: Study of diagnostic accuracy. SETTING: Molecular diagnostics laboratories in three hospitals. PATIENT(S): A total of 701 men with nonobstructive azoospermia or oligozoospermia from three hospitals. INTERVENTION(S): We developed a quadruplex real-time polymerase chain reaction (PCR) assay and...
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