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Article

Common TMPRSS6 mutations and iron, erythrocyte, and pica phenotypes in 48 women with iron deficiency or depletion.

Blood cells, molecules & diseases - 15 Feb 2012

Lee Pauline L, Barton J Clayborn, Khaw Peter L, Bhattacharjee Sarah Y, Barton James C

Abstract excerpt

BACKGROUND: TMPRSS6 A736V is associated with lower transferrin saturation (TS), hemoglobin (Hb), and mean corpuscular volume (MCV) levels in general adult populations. We sought to identify relationships of TMPRSS6 K253E, A736V, and Y739Y to iron, erythrocyte, and pica phenotypes in women with iron deficiency or depletion. METHODS: We tabulated observations on 48 outpatient non-pregnant women who had iron...

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Identifiers

PMID: 22265928
DOI: 10.1016/j.bcmd.2011.12.003
PMCID: PMC3271795

Genes

TMPRSS6

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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