Article
A high density SNP array for the domestic horse and extant Perissodactyla: utility for association mapping, genetic diversity, and phylogeny studies.
PLoS genetics - 1 Jan 2012
McCue Molly E, Bannasch Danika L, Petersen Jessica L, Gurr Jessica, Bailey Ernie, Binns Matthew M, Distl Ottmar, Guérin Gérard, Hasegawa Telhisa, Hill Emmeline W, Leeb Tosso, Lindgren Gabriella, Penedo M Cecilia T, Røed Knut H, Ryder Oliver A, Swinburne June E, Tozaki Teruaki, Valberg Stephanie J, Vaudin Mark, Lindblad-Toh Kerstin, Wade Claire M, Mickelson James R
Abstract excerpt
An equine SNP genotyping array was developed and evaluated on a panel of samples representing 14 domestic horse breeds and 18 evolutionarily related species. More than 54,000 polymorphic SNPs provided an average inter-SNP spacing of ∼43 kb. The mean minor allele frequency across domestic horse breeds was 0.23, and the number of polymorphic SNPs within breeds ranged from 43,287 to 52,085. Genome-wide linkage...
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