Article
Dominance of multidrug resistant CC271 clones in macrolide-resistant streptococcus pneumoniae in Arizona.
BMC microbiology - 18 Jan 2012
Bowers Jolene R, Driebe Elizabeth M, Nibecker Jennifer L, Wojack Bette R, Sarovich Derek S, Wong Ada H, Brzoska Pius M, Hubert Nathaniel, Knadler Andrew, Watson Lindsey M, Wagner David M, Furtado Manohar R, Saubolle Michael, Engelthaler David M, Keim Paul S
Abstract excerpt
BACKGROUND: Rates of resistance to macrolide antibiotics in Streptococcus pneumoniae are rising around the world due to the spread of mobile genetic elements harboring mef(E) and erm(B) genes and post-vaccine clonal expansion of strains that carry them. RESULTS: Characterization of 592 clinical isolates collected in Arizona over a 10 year period shows 23.6% are macrolide resistant. The largest portion of the...
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