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Article

Molecular basis and clonal nature of increasing pneumococcal macrolide resistance in South Africa, 2000-2005.

International journal of antimicrobial agents - 1 Jul 2008

Wolter Nicole, von Gottberg Anne, du Plessis Mignon, de Gouveia Linda, Klugman Keith P

Abstract excerpt

The prevalence and molecular epidemiology of pneumococcal macrolide resistance in South Africa was investigated. Minimum inhibitory concentrations and serotypes of pneumococcal isolates causing invasive disease from 2000-2005 (n=15982), collected through a national laboratory-based surveillance system, were determined. Randomly selected isolates from 2005 (51%; 260/508) had resistance mechanisms determined, and...

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PMID: 18339522
DOI: 10.1016/j.ijantimicag.2008.01.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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