Relationship between advanced oxidation protein products, advanced glycation end products, and S-nitrosylated proteins with biological risk and MDR-1 polymorphisms in patients affected by B-chronic lymphocytic leukemia.

doi:10.3109/07357907.2011.629383

Article

Relationship between advanced oxidation protein products, advanced glycation end products, and S-nitrosylated proteins with biological risk and MDR-1 polymorphisms in patients affected by B-chronic lymphocytic leukemia.

Cancer investigation - 1 Jan 2012

Gangemi Sebastiano, Allegra Alessandro, Aguennouz Mohamed, Alonci Andrea, Speciale Antonio, Cannavò Antonino, Cristani Mariateresa, Russo Sabina, Spatari Giovanna, Alibrandi Angela, Musolino Caterina

Abstract excerpt

The aim of our study was to analyze the serum levels of advanced oxidation protein products (AOPPs) and advanced glycation end products (AGEs), and protein nitrosylation in patients with B-chronic lymphocytic leukemia (B-CLL). AOPPs, AGEs, and S-nitrosylated were increased in B-CLL patients. The mutation of IgVH gene, CD 38, and Zap 70 expression were not associated with increased oxidative stress. The mutant...

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