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Article

Polymorphism discovery and allele frequency estimation using high-throughput DNA sequencing of target-enriched pooled DNA samples.

BMC genomics - 11 Jan 2012

Mullen Michael P, Creevey Christopher J, Berry Donagh P, McCabe Matt S, Magee David A, Howard Dawn J, Killeen Aideen P, Park Stephen D, McGettigan Paul A, Lucy Matt C, Machugh David E, Waters Sinead M

Abstract excerpt

BACKGROUND: The central role of the somatotrophic axis in animal post-natal growth, development and fertility is well established. Therefore, the identification of genetic variants affecting quantitative traits within this axis is an attractive goal. However, large sample numbers are a pre-requisite for the identification of genetic variants underlying complex traits and although technologies are improving...

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PMID: 22235840
DOI: 10.1186/1471-2164-13-16
PMCID: PMC3315736

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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