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Article

Mapping of quantitative trait loci controlling lifespan in the short-lived fish Nothobranchius furzeri--a new vertebrate model for age research.

Aging cell - 1 Apr 2012

Kirschner Jeanette, Weber David, Neuschl Christina, Franke Andre, Böttger Marco, Zielke Lea, Powalsky Eileen, Groth Marco, Shagin Dmitry, Petzold Andreas, Hartmann Nils, Englert Christoph, Brockmann Gudrun A, Platzer Matthias, Cellerino Alessandro, Reichwald Kathrin

Abstract excerpt

The African annual fish Nothobranchius furzeri emerged as a new model for age research over recent years. Nothobranchius furzeri show an exceptionally short lifespan, age-dependent cognitive/behavioral decline, expression of age-related biomarkers, and susceptibility to lifespan manipulation. In addition, laboratory strains differ largely in lifespan. Here, we set out to study the genetics of lifespan...

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PMID: 22221414
DOI: 10.1111/j.1474-9726.2011.00780.x
PMCID: PMC3437503

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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