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Article

[Mutations in insulin-like growth factor receptor 1 gene (IGF1R) resulting in intrauterine and postnatal growth retardation].

Arquivos brasileiros de endocrinologia e metabologia - 1 Nov 2011

Leal Andréa de Castro, Canton Ana Pinheiro Machado, Montenegro Luciana Ribeiro, Coutinho Débora Cabral, Arnhold Ivo Jorge Prado, Jorge Alexander Augusto de Lima

Abstract excerpt

Approximately 10% of children born small-for-gestational age (SGA) do not show spontaneous growth catch-up. The causes of this deficit in prenatal growth and its maintenance after birth are not completely known, in most cases. Over the past eight years, several heterozygous inactivating mutations and deletions in IGF1R gene have been reported, indicating the role of defects in the IGFs/IGF1R axis as a cause of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22218435
DOI: 10.1590/s0004-27302011000800007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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