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Article

Familial short stature with IGF-I receptor gene anomaly [Review]

19 Oct 2011

Abstract excerpt

Type I insulin-like growth factor receptor (IGF-IR) is widely expressed across many cell types in fetal and postnatal tissues. The activation of this receptor after the binding of secreted IGF-I and IGF-II promotes cell differentiation and proliferation. IGF-IR has an important role in normal fetal and postnatal growth and development. IGF-IR gene anomalies presenting with intrauterine and postnatal growth...

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Identifiers

PMID: 22008389
DOI: 10.1507/endocrj.ej11-0258

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