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Nanotube Action between Human Mesothelial Cells Reveals Novel Aspects of Inflammatory Responses

27 Dec 2011

Abstract excerpt

A well-known role of human peritoneal mesothelial cells (HPMCs), the resident cells of the peritoneal cavity, is the generation of an immune response during peritonitis by activation of T-cells via antigen presentation. Recent findings have shown that intercellular nanotubes (NTs) mediate functional connectivity between various cell types including immune cells - such as T-cells, natural killer (NK) cells or...

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PMID: 22216308
DOI: 10.1371/journal.pone.0029537

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