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Article

A model of genetic search for beneficial mutations: estimating the constructive capacities of mutagenesis.

Journal of molecular evolution - 1 Dec 2011

Ananko Grigory G

Abstract excerpt

We attempted to answer the following question: What evolutionary conditions are required to generate novel genetic modules? Our broad formulation of the problem allows us to simultaneously consider such issues as the relationship between the stage of "genetic search" and the rate of adaptive evolution; the theoretical limits to the generative capacities of spontaneous mutagenesis; and the correlation between...

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PMID: 22212997
DOI: 10.1007/s00239-011-9482-z

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