Article
Localization, expression change in PRRSV infection and association analysis of the porcine TAP1 gene.
International journal of biological sciences - 1 Jan 2012
Sun Nunu, Liu Dewu, Chen Hongbo, Liu Xiangdong, Meng Fanming, Zhang Xianwei, Chen Huiyong, Xie Shengsong, Li Xinyun, Wu Zhenfang
Abstract excerpt
The transporter associated with antigen processing (TAP) translocates antigenic peptides from the cytosol into the lumen of the endoplasmic reticular and plays a critical role in the major histocompatibility complex (MHC) class I molecule-mediated antigenic presentation pathway. In this study, the porcine TAP1 gene was mapped to the pig chromosome 7 (SSC7) and was closely linked to the marker SSC2B02 (retention...
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