Article
Identification of novel genes associated with atherosclerosis in Bama miniature pig.
Animal models and experimental medicine - 1 Jun 2024
Ding Dengfeng, Zhao Yuqiong, Jia Yunxiao, Niu Miaomiao, Li Xuezhuang, Zheng Xinou, Chen Hua
Abstract excerpt
BACKGROUND: Atherosclerosis is a chronic cardiovascular disease of great concern. However, it is difficult to establish a direct connection between conventional small animal models and clinical practice. The pig's genome, physiology, and anatomy reflect human biology better than other laboratory animals, which is crucial for studying the pathogenesis of atherosclerosis. METHODS: We used whole-genome sequencing...
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